Proteins play a critical role in cellular function by interacting with other biomolecules; missense variants that cause loss of protein function can lead to a broad spectrum of genetic disorders.

In 2008, power over our financial markets and economy was ceded to the Federal Reserve and it's extraordinary monetary policy. Perhaps its time to scale it back.

Stanley is an associate professor and Richard and Rhoda Goldman distinguished chair in the biological sciences as well as faculty director for the Alliance for Global Health and Science at the ...

This site displays a prototype of a “Web 2.0” version of the daily Federal Register. It is not an official legal edition of the Federal Register, and does not replace the official print version or the ...

Cytokine release syndrome occurred in 33 and 24% of participants in the ATG 2.5- and 0.5mg/kg groups, respectively, and in no participants in the placebo group. HealthDay News — Antithymocyte globulin ...

Mutations that activate phosphorylation of certain Rab GTPases by LRRK2 have been linked to a subset of genetic cases of Parkinson’s disease, and PPM1M is one of the phosphatases responsible for ...

In patients with lupus nephritis, histology and baseline kidney function predict eGFR decline. In patients with lupus nephritis (LN), low baseline estimated glomerular filtration rate (eGFR) and ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) The term “gain of function” is often taken to refer to research with viruses that puts ...

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating ...