Clinical depression is considered one of the most treatable mood disorders, but neither the condition nor the drugs used against it are fully understood. First-line SSRI treatments (selective ...

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human ...

Using a new kind of neuroimaging tool, researchers have uncovered evidence to help explain how antidepressant medications work, and why they take so many weeks to kick in. For the last few decades the ...

BARCELONA — The typical lag between treatment initiation with selective serotonin reuptake inhibitors (SSRIs) for depression and enhanced mood may be because of the time it takes to increase brain ...

Firstly, it indicates that SSRIs increase synaptic density in the brain areas critically involved in depression. This would go some way to indicating that the synaptic density in the brain may be ...

For many individuals battling the darkness of depression, antidepressants are a ray of hope. These medications, known as selective serotonin reuptake inhibitors (SSRIs), offer relief but come with a ...

Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...

The mechanisms by which antidepressants and other emotion-focused medications work could be reconsidered due to an important new breakthrough in the understanding of how the gut communicates with the ...

People who have pulled an all-nighter may be familiar with that “tired and wired” feeling. Although the body is physically exhausted, the brain feels slap-happy, and almost giddy. Northwestern ...

Related: 1 psychedelic psilocybin dose eases depression for years, study reveals Normally, the brain processes sensory information via lower-level networks and then feeds that "up the chain" to higher ...