Clinical depression is considered one of the most treatable mood disorders, but neither the condition nor the drugs used against it are fully understood. First-line SSRI treatments (selective ...

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human ...

Using a new kind of neuroimaging tool, researchers have uncovered evidence to help explain how antidepressant medications work, and why they take so many weeks to kick in. For the last few decades the ...

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine ...

If you or someone you know is taking medicine to treat depression, it might be a selective serotonin uptake inhibitor — more commonly referred to as an SSRI. SSRIs are the most commonly prescribed ...

Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed medications in the United States, primarily for managing depression. While SSRIs emerged as antidepressants during ...

In the first directive since his nomination for secretary of health and human services, Robert F. Kennedy Jr. thrust psychiatric medications and their use among children into the national spotlight.

Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...

In the 1980s, people generally thought of depression as a meaningful response to a crisis. A job loss. A divorce. Struggling to fit in at school. The angst of realizing life didn’t turn out as you’d ...