The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...

Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...

A groundbreaking study reveals that human cells initiate self-destruction processes when viruses disrupt RNA production, offering new insights into innate antiviral defenses. Conducted and reported on ...

RNA is thought to be a stay-at-home kind of molecule, often comfortably confined within the cell’s interior. So, when RNA molecules were detected on the surface of several cell types, researchers ...

Small ribozymes such as Oryza sativa twister spontaneously cleave their own RNA when the ribozyme folds into its active conformation. The coupling between twister folding and self-cleavage has been ...

A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...