引言在体内，酶 (enzyme) 常常被认为是最勤奋、最高效的工匠。它们以惊人的速度和精度催化着几乎所有的生物化学反应，从食物的消化到DNA的复制，无处不在。长期以来，理解并预测特定酶会与哪种底物 (substrate) 结合，即酶的底物特异性 ...

How an enzyme activates its substrate for turnover is fundamental for catalysis but incompletely understood on a structural level. With redox enzymes one typically analyses structures of ...

image: Enzyme substrate specificity involving material conversion processes is pertinent to e.g. biochemistry, metabolic engineering, and environmental remediation; however, it is one of the most ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

Mechanistically, the chemists think that in the presence of the enzyme, there’s a formal hydrogen atom abstraction that is ...

Biological cells invest much of their resources into the production of enzymes, which catalyze the conversion of substrates into products. An international team of bioinformaticians and biophysicists ...

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, ...

Enzymes are essential for life and are one of the most important types of protein in the human body. Studying enzyme kinetics provides information about the diverse range of reactions in the human ...

By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative ...

Enzyme kinetics involves the measurement of the rate at which chemical reactions that are catalyzed by enzymes occur. Knowledge about the kinetics of an enzyme can reveal useful information about its ...