Activating the GPR133 receptor with a small molecule can rebuild bone from within, offering a new direction for osteoporosis ...
A Hall-effect sensor is a transducer that converts a magnetic field directly into a usable electrical voltage. It enables ...
BOOSTER是一项多中心、随机、Ⅱ期临床研究,旨在评估消融联合免疫治疗在免疫治疗后出现寡残留病灶的晚期NSCLC患者中的疗效与安全性。研究共筛选618例接受一线免疫治疗的晚期非小细胞肺癌患者,共65例患者纳入研究,2:1随机分配至消融联合组与免疫维 ...
By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative enzyme switch called "Switchbody," which is activated when bound to its ...
为探究母体胆固醇水平与后代心脏发育之间的因果关系,研究人员建立了母体低胆固醇小鼠模型。他们给8周龄ICR雌鼠喂食含有依折麦布或阿托伐他汀的饲料,这两种药物分别通过抑制肠道胆固醇吸收和内源性合成来降低胆固醇水平。
免疫治疗药物的问世革命性地改变了晚期NSCLC的治疗格局。这些药物通过阻断PD-1/PD-L1通路,解除肿瘤对免疫细胞的抑制,显著延长了部分患者的生存期。然而,仅约20%的患者对免疫治疗有持续反应。超过80%的患者最终会产生耐药性,导致疾病进展。尤其 ...
本周,国内高校在国际顶级期刊持续发表高水平研究论文,多个院士团队开创新成果,展现科研创新活力! 1. Cell Death Differ丨防治心脏纤维化及心力衰竭取得新进展 2025 年 11 月 6 ...
Novel trial designs like basket, umbrella, and platform trials enhance efficiency and reduce development timelines in precision medicine. Basket trials test a single therapy across different tumor ...
Eli Lilly will partner with Insilico Medicine on an artificial intelligence (AI)-based drug development collaboration that they said could generate “over $100 million” for the AI drug discovery ...
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