Understanding how morphogens promote three-dimensional patterning is an important issue in developmental biology. Recently, new insights have been gained into the mechanisms by which the Drosophila ...

Primary cilia function as specialized compartments for signal transduction. The stereotyped structure and signaling function of cilia inextricably depend on the selective segregation of molecules in ...

Sticky spots on cell membranes hold onto the master regulator of cell polarity, helping to ensure that the regulatory protein accumulates in high enough concentrations to trigger cell polarity. Over ...