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26 天
Vutiglabridin作为PON2调节剂在帕金森病临床前模型中的神经治疗作用研究
本研究针对帕金森病治疗中氧化应激和线粒体功能障碍等关键病理环节,首次系统评价了新型小分子药物Vutiglabridin通过调节Paraoxonase-2(PON2)发挥神经保护作用的机制。研究人员发现Vutiglabridin能有效穿透血脑屏障,在MPP+诱导和α-syn A53T过表达的PD模型中显著改善线 ...
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