By profiling over 16 million immune cells from people aged 22 to 65 after flu vaccination, scientists discovered that memory T cell function changes with age.

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...

Pre-wired ability in ‘resting’ T cells to remember past viral foes discovered, a promising breakthrough for targeted cancer therapies. A team of immunologists at the University of Massachusetts ...

Researchers at the University of Colorado Anschutz Medical Campus have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with ...

SEATTLE — Tissue resident memory (TRM) T cells are a hot topic lately in the treatment of psoriasis. These cells reside in the skin and other tissues and promote the inflammatory response, likely ...

T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers.

Monash University researchers used CRISPR or a PTPN2 inhibitor to enhance CAR T cell function against solid tumors. Blocking ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...