Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

The aim of this research therefore was to streamline the understanding of typical causal structures in both randomized and nonrandomized clinical trials in oncology, presenting concise guidelines for ...

The World Health Organization recommends 1500 to 2000 mg of calcium daily as supplementation, divided into three doses, for pregnant persons in populations with low dietary calcium intake in order to ...

The equipoise randomization strategy allowed patients to indicate a preference to which of the level 2 options they would accept or refuse. Only 1% of the cohort would accept all 7 treatment options.

For more than three decades, researchers Christine Stabell Benn and Peter Aaby from the Bandim Health Project have conducted randomized trials involving thousands of children in Guinea-Bissau and ...

Randomized phase II trial of neoadjuvant androgen deprivation therapy plus abiraterone and apalutamide for patients with high-risk localized prostate cancer: Pathologic response and PSMA imaging ...