Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is ...

A series of structures of the eukaryotic protein-synthesis machinery are imaged at high resolution in defined states of the elongation phase of protein synthesis. Analysis suggests that there are ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

A group of scientists has succeeded in the development of modified messenger RNAs (mRNAs) that contain sulfur atoms in the place of oxygen atoms of phosphate moieties of natural mRNAs. They discovered ...

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired. In particular, mRNA therapeutics hold the potential for ...

Chemists have developed a protocol to rapidly produce protein chains up to 164 amino acids long. The flow-based technology could speed up drug development and allow scientists to design novel protein ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

It is well known that many strains of Staphylococcus are resistant to antibiotics, and research groups around the world seek new targets in the bacteria to decrease their infectious potential. The ...

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the ...