The usual methodology employed in analysis after a sequential clinical trial is based on orderings of the possible samples resulting from the design. However, this approach lacks flexibility for use ...

The number needed to treat, that is, the average number of patients a clinician needs to treat with a particular therapy to prevent one bad outcome,1 is a translation into clinical terms of the ...

Strong Lagrangian theory is used to illuminate the properties of the profile log likelihood. General conditions are given which lead to a simplification of the computations required to plot this ...

The course provides a precise and accurate treatment of statistical ideas, methods and techniques. Topics covered are sampling distributions of statistics, point estimation, interval estimation, ...

The course provides a precise and accurate treatment of statistical ideas, methods and techniques. Topics covered are sampling distributions of statistics, point estimation, interval estimation, ...

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