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2013年至2023年间,中国北京地区临床患者中EBV DNA的检测情况
EBV DNA阳性率在PUMCH 2013-2023年波动,男性及高龄组(≥71岁)阳性率显著更高,2020-2022年因疫情影响阳性率骤降。152例IM患者中,肝功能异常(ALT/AST升高)发生率57%-59%,免疫激活标志物(CD8+DR+/CD8+升高、CD19+B细胞减少)达99%-90%,证实EBV感染与IM相关,且免疫失衡是主要病理特征。
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