Gene amplifications and deletions frequently have pathogenetic roles in cancer. 30,000 radiation-hybrid mapped cDNAs provide a genomic resource to map these lesions with high resolution. We developed ...

A single microarray can provide information on the expression of tens of thousands of genes. The amount of information generated by a microarray-based experiment is sufficiently large that no single ...

Behind closed doors, countless Kenyan women face the repeated trauma of miscarriage, a silent, isolating experience. Margaret Nyawira knows this grief better than most: She suffered four miscarriages ...

This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...