ncRNA通过多层面驱动耐药的机制，为破局抗HER2治疗困境提供了新视角。人类表皮生长因子受体2（HER2）是乳腺癌、胃癌等多种恶性肿瘤中至关重要的驱动基因和生物标志物。它的过度表达或扩增，与肿瘤的侵袭性增强和不良预后密切相关。曲妥珠单抗作为首个针对 ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in ...

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun ...

Researchers from Stockholm University extracted the RNA sequences from a juvenile mammoth (named Yuka) that died almost ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

A new University of Chicago study explores how prolonged exposure to ultraviolet (UV) radiation can trigger inflammation in skin cells through degradation of a key protein called YTHDF2. This protein ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

Smaller noncoding RNA is being used in clinical practice and as knowledge grows of long noncoding RNA, use of it should follow, explained Laura Denby, PhD, Kidney Research UK Senior Fellow, senior ...

TORINO, Italy--(BUSINESS WIRE)--Resalis Therapeutics today announced its completion of the seed financing round of €10 million to establish a non-coding RNA (ncRNA)-based therapeutic approach for the ...