Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation.

Abstract: A conceptual framework, I-AMS-IC (Intelligent Analog and Mixed-Signal IC), is proposed to enable automation in analog/mixed-signal (AMS) design by integrating machine learning with an ...

Introduction: Voriconazole is widely used to prevent and treat invasive aspergillosis. However, its use is restricted by adverse effects, including acute liver injury (ALI). Patients with hepatic ...

Systemic estrogen replacement therapy is contraindicated in women with a history of ischemic stroke due to the risk of stroke recurrence. There are currently no published data available describing the ...

Per- and polyfluoroalkyl substances (PFAS) exposure is linked to a 31% increased risk of type 2 diabetes (T2D), with perfluorooctane sulfonate being a significant contributor. Metabolomic profiling ...

Copyright: © 2025 The Author(s). Published by Elsevier Ltd. Women benefit from reduced fracture risk while using menopausal hormone therapy. However, information on ...

Department of Endocrinology and Metabolism, Central Hospital of Dalian University of Technology, Dalian Municipal Central Hospital, Dalian, Liaoning, China Objective: This study aimed to investigate ...

Department of Medical Records, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu, P. R. China Department of Epidemiology and Health Statistics, School of Public Health, Lanzhou ...

ABSTRACT: Background and Objective: The peri-anaesthetic management of an elderly patient is significantly different from that of a young patient. This study was conducted to determine the morbidity ...