A newly discovered CPD gene mutation causes hearing loss, and scientists found that Viagra and arginine may help reverse it.

Common ancestor eels lost the aquaporin gene encoding proteins with broad solute permeability. Researchers from the Institute ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Adults with a loss-of-function mutation in the MC4R gene ...

Restoring P53's autonomous anti-cancer function through P53 mRNA delivery is a promising anti-tumor strategy. Yet, in tumors harboring mutant P53, the existing mutant P53 (Mutp53) would interferes ...

Targets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules, monoclonal antibodies, RNAi, and CRISPR gene editing therapies.

Melanocortin-4-receptor MC4R is a crucial molecule involved in energy homeostasis, feeding behavior and metabolism, and loss-of-function mutations in this gene are the main monogenic cause of ...

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across ...

Outcomes in patients with pancreatic and ampullary cancer whose tumors harbor pathogenic APC mutations. Utility of circulating tumor DNA (ctDNA) for the detection of minimal residual disease (MRD) ...

Autologous T-Cell Therapies in Solid Tumor Malignancies: Current Landscape and Future Opportunities Histology-agnostic therapies: by focusing on common mutations across various cancers, this approach ...

A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn's disease can worsen iron deficiency and anemia - ...