The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new ...

Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.

Researchers from the School of Dental Medicine and international collaborators from Dresden Germany investigated the effects of training the innate immune system in experimental models of chronic ...

Researchers at the University of Kansas have discovered a human gene, the protein PARP14, plays a role in regulating ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Researchers at the University of Kansas have discovered a human gene, the protein PARP14, plays a role in regulating ...

Inflammation is a critical component of the immune response that plays a pivotal role in maintaining tissue homeostasis.

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the ...

Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life, presumably even in ...