Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disorder globally, with a rising ...

The authors have proposed the Microbiota-derived metabolites–epigenetics (MDME) axis, a conceptual framework explaining how microbial metabolites function as a critical link between the environment ...

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is the main finding of the latest research by Dr. Marcus Buschbeck and Dr.

This article explores how epigenetic mechanisms control gene expression, how their disruption drives cancer and how targeting ...

Targeting a specialized group of histones is safe and opens new therapeutic opportunities for treating blood cancers. This is ...

Discover how a simple shift toward spermidine-rich foods can activate your body’s natural cellular renewal system, protecting ...

Stem cells possess the unique abilities of self-renewal and differentiation into various cell types, making them highly ...

Peer-reviewed study in Cell Reports Medicine demonstrates that N17350 delivers selective, immune-activating tumor killing across solid tumor types -- N17350 targets a cancer vulnerability, via the ...