Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mycobacterium tuberculosis causes long-term ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Many transcriptional and post-transcriptional mechanisms control gene expression in eukaryotic cells. The zinc finger antiviral protein (ZAP) is induced by interferon and inhibits viral gene ...

School of Integrative Biological and Chemical Sciences (SIBCS), University of Texas Rio Grande Valley (UTRGV), Edinburg, TX, United States Understanding embryonic patterning, the process by which ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, ...