The discovery of the DNA structure sparked a flurry of new research, birthing fields like molecular biology, biotechnology, ...

Structure Maintenance of Chromosome (SMC) complexes are central to chromosome segregation, compaction and DNA repair, thereby impacting on gene expression and regulation. SMC family members that ...

Conventional CRISPR–Cas systems maintain genomic integrity by leveraging guide RNAs for the nuclease-dependent degradation of mobile genetic elements, including plasmids and viruses. Here we describe ...

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.