Virtual screening methods fall broadly into two categories: ligand- and structure-based. Ligand-based virtual screening doesn’t require a target protein structure, Instead, it leverages known active ...

Stomach cancer, or gastric cancer, is the third leading cause of cancer deaths worldwide, largely because most individuals are not diagnosed until after the cancer has progressed to a late stage.

Molecular glue degraders (MGDs) are a powerful approach to target proteins traditionally considered ‘undruggable’. By harnessing the ubiquitin–proteasome system, they can induce protein degradation ...

Leiden researchers, led by Sebastian Pomplun, have developed a new method to screen hundreds of thousands of molecules for ...

Introduction Body image disturbance (BID) is a complex construct that includes cognitive-affective, perceptual and behavioural characteristics, influencing how people perceive and feel about their ...

Kentucky has one of the highest rates of colorectal cancer in the US, but early detection leads to a 91% five-year survival rate. Colorectal cancer is projected to become the leading cancer killer for ...

The Ulysses S. Grant Presidential Library, in partnership with Mississippi Public Broadcasting, will host a special screening of the new Ken Burns documentary on the American Revolution on Oct. 21 at ...

Chloroplasts—the "light power plants" of plant cells—are increasingly the focus of synthetic biology. These organelles house ...

The pharmaceutical industry widely uses antibodies to create drugs, such as for cancer and coronaviruses. But creating the ...

This article explores how advances in automation, 3D cell models and AI are transforming high-throughput screening, driving ...