ncRNA通过多层面驱动耐药的机制,为破局抗HER2治疗困境提供了新视角。人类表皮生长因子受体2(HER2)是乳腺癌、胃癌等多种恶性肿瘤中至关重要的驱动基因和生物标志物。它的过度表达或扩增,与肿瘤的侵袭性增强和不良预后密切相关。曲妥珠单抗作为首个针对 ...
The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...
Although evolution awarded us with appendages and complex sensory systems, the human body, much like a worm, is simply a large tube transporting food from one end to the other. It is hard to imagine ...
Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring ...
A joint research team has discovered a new molecular switch that determines when plant leaves begin to age. The research team has identified for the first time a new mechanism in which RNA made from ...
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring ...
Researchers disagree on the number of genes in the human genome, in part because what exactly a gene is can be difficult to determine. Upregulation of a specific microRNA in the brain lessened anxiety ...