ncRNA通过多层面驱动耐药的机制，为破局抗HER2治疗困境提供了新视角。人类表皮生长因子受体2（HER2）是乳腺癌、胃癌等多种恶性肿瘤中至关重要的驱动基因和生物标志物。它的过度表达或扩增，与肿瘤的侵袭性增强和不良预后密切相关。曲妥珠单抗作为首个针对 ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

Although evolution awarded us with appendages and complex sensory systems, the human body, much like a worm, is simply a large tube transporting food from one end to the other. It is hard to imagine ...

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding ...

本综述深入探讨了具核梭杆菌（Fusobacterium nucleatum）与宿主非编码RNA（ncRNAs）在结直肠癌（CRC）中的复杂互作机制。文章系统 ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

TORINO, Italy--(BUSINESS WIRE)--Resalis Therapeutics today announced its completion of the seed financing round of €10 million to establish a non-coding RNA (ncRNA)-based therapeutic approach for the ...