Boosting levels of a certain molecule that declines with age was found to restore memory and brain function in Alzheimer’s ...

Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a ...

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a ...

RNA splicing involves the removal of non-coding introns and the joining of coding exons in precursor mRNA (pre-mRNA) to produce mature messenger RNA (mRNA). Splicing changes can lead to diseases, ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading. However, many individuals develop resistance to few ...

Key opportunities in the RNA targeting small molecules therapeutics market include growth in RNA splicing modifications, neurodegenerative diseases, drug discovery, and pharma-biotech sectors.

CSHL’s Krainer lab used a technique called live-cell fluorescence imaging to observe the DDX23 enzyme (above, in green) in action. Together with the critical regulator protein SRSF1, DDX23 helps set ...

Teresa Rodriguez-Martin, Mariano A. Garcia-Blanco, S. Gary Mansfield, Andrew C. Grover, Michael Hutton, Qingming Yu, Jianhua Zhou, Brian H. Anderton, Jean-Marc Gallo Proceedings of the National ...