Cyclone is a portable gene-switch system that uses acyclovir to reversibly control gene expression with minimal toxicity.

Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study ...

If our genes are so similar, what really makes a eukaryote different from a prokaryote, or a human from E. coli? The answer lies in the difference in gene expression and regulation used. Regulation of ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Research from UChicago dissects how a single genetic switch helps butterflies mimic wing patterns of other species to protect ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Researchers have discovered that a gene called CHRNA3 plays a key role in determining alcohol sensitivity, helping explain why some people tolerate alcohol better than others.