During protein synthesis, the genetic information stored in DNA is first transcribed into mRNA. The mRNA then travels to the ribosome, where translation occurs. Here's how anticodons facilitate the ...

During decoding, a codon of messenger RNA is matched with its cognate aminoacyl-transfer RNA and the amino acid carried by the tRNA is added to the growing protein chain. Here we propose a molecular ...

This is a preview. Log in through your library . Abstract During transfer RNA (tRNA) selection, a cognate codon:anticodon interaction triggers a series of events that ultimately results in the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 74, No. 1 (Jan., 1977), pp. 198-202 (5 pages) The fidelity of protein synthesis is substantially greater than the ...

Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gene therapy ...

In a new study, researchers at the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact used start codon disruption with CRISPR-Cas9 gene editing to prevent Fuchs' ...

The history of biomarker development for epidermal growth factor receptor (EGFR) monoclonal antibodies for patients with colorectal cancer has been a convoluted path. Each development has provided ...