Research in gene therapy involving genome-integrating vectors now often includes analysis of vector integration sites across the genome using methods such as ligation-mediated PCR (LM-PCR) or linear ...
Foamy virus (FV) vectors are an alternative type of retroviral vector with a large packaging capacity, 16 wide host range, 17 and a complementary DNA genome. 18, 19 FV vectors may be less oncogenic ...
Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have performed a large-scale analysis of FV ...