tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

As the area of small molecules interacting with RNA advances, general routes to provide bioactive compounds are needed as ligands can bind RNA avidly to sites that will not affect function.

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department ...

The Series A round of funding announced Wednesday was led by a syndicate that includes ARCH Venture Partners, Takeda Ventures, and 8VC. The cause of many diseases are ...

Study reveals how an RNA enzyme drives the postnatal switch from glucose to fatty acids in heart cells, highlighting ketogenesis as essential for metabolism. Study: The tRNA methyltransferase Mettl1 ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function of regulatory T cells in the immune system. As their name suggests, ...