Ángel Rentería-Gómez is in the Department of Chemistry, Texas A&M University, College Station, Texas 77842, USA. Access to large libraries of analogues of drug candidates, with varied structural ...

Collections of small molecules are used routinely in high-throughput screens to find new drug leads. In fact, from 1999 to 2008, 45 of the 50 Food and Drug Administration approvals for first-in-class ...