under H 0 and H 1, respectively, where n represents the total sample size in the study (cases and controls). M 0 (n,k) is analogous to a type I error, yet is not fixed by design at α. M i (n,k) i=0,1 ...

We present a simple sample-size formula for weighted log-rank statistics applied to clustered survival data with variable cluster sizes and arbitrary treatment assignments within clusters. This ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

A statistical model developed from scientific theory may "fail to fit" the available data if the scientific theory is incorrect or if the sample size is too small. The former point is obvious but the ...

Sample size (the number of individuals examined for a study) is the most important factor determining the accuracy of the study results. The accuracy and reproducibility of research studies are a ...

Jason Fernando is a professional investor and writer who enjoys tackling and communicating complex business and financial problems. Erika Rasure is globally-recognized as a leading consumer economics ...

NEW HAVEN, Conn., July 13, 2020 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company focused on the development and commercialization of Haduvio ...

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...