When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in ...
ncRNA通过多层面驱动耐药的机制,为破局抗HER2治疗困境提供了新视角。人类表皮生长因子受体2(HER2)是乳腺癌、胃癌等多种恶性肿瘤中至关重要的驱动基因和生物标志物。它的过度表达或扩增,与肿瘤的侵袭性增强和不良预后密切相关。曲妥珠单抗作为首个针对 ...
Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...
circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...
Various sayings equate going fast with going alone. But none of them apply to the gene expression journey described by a research team from the University of Göttingen. The team, led by Heike Krebber, ...
Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun ...
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.
Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can ...
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring ...
A joint research team has discovered a new molecular switch that determines when plant leaves begin to age. The research team has identified for the first time a new mechanism in which RNA made from ...