When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in ...

ncRNA通过多层面驱动耐药的机制，为破局抗HER2治疗困境提供了新视角。人类表皮生长因子受体2（HER2）是乳腺癌、胃癌等多种恶性肿瘤中至关重要的驱动基因和生物标志物。它的过度表达或扩增，与肿瘤的侵袭性增强和不良预后密切相关。曲妥珠单抗作为首个针对 ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

Various sayings equate going fast with going alone. But none of them apply to the gene expression journey described by a research team from the University of Göttingen. The team, led by Heike Krebber, ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss ...

RNA，作为细胞信号传导的重要使者，在许多疾病中扮演着重要的角色，无论是神经退行性疾病还是衰老，都有研究者在开发相应的RNA疗法。 西湖大学讲席教授付向东自1992年建实验室时起，就一直在做RNA方面的基础研究和转化应用。他于2010年入选美国科学促进会 ...

Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring ...

A joint research team has discovered a new molecular switch that determines when plant leaves begin to age. The research team has identified for the first time a new mechanism in which RNA made from ...