Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

Proteins are life’s engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

Researchers from the University of Tokyo and Juntendo University have identified a previously unknown structural domain in ...

Amyloids are perhaps best known as a key driver of Alzheimer’s disease. The amorphous proteins, found throughout the human body, stick to nerve cells like plaque, choking off their function and ...

Hormones coordinate different body functions by carrying messages through the bloodstream to target cells and tissues. Hormonal imbalances occur through inadequate or excess hormone synthesis, which ...

Within the past few years, models that can predict the structure or function of proteins have been widely used for a variety of biological applications, such as identifying drug targets and designing ...

A multicolored protein structure is blurred at the edges and comes into focus toward the center. Detail of a protein designed using a tool called ProteinMPNN Credit: Ian C. Haydon/UW Institute for ...