综上所述，这项研究描绘了一条精妙的肠道-大脑防御通路：在经历分解代谢挑战后的恢复期，摄入富含谷氨酰胺、赖氨酸和苏氨酸的蛋白质，会在肠道（尤其是十二指肠）产生大量氨；肠道嗜铬细胞通过其表面的TRPA1受体感知到这种氨负荷后，释放血清素；血清素信号继而通 ...

This study provides valuable insights into the role of the NF-kB and IKK signaling pathways in γδ T cell development and survival, using robust genetic mouse models. While the research is ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and ...

After an illness like the flu, symptoms may go away while a person still feels lousy. Researchers wanted to learn more about ...

Cell movement is an essential biological process, whether it's cancer cells metastasizing to other parts of the body or ...

The transcription factor HEB synergizes with TCR signaling to upregulate Id3, which is required for the maturation of fetal IL-17-producing γδ T cells.

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Scientists have discovered how the amino acid leucine boosts the body’s energy production by protecting key mitochondrial ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...