Genetic diseases that result from truncated proteins can be targeted by so-called nonsense suppression therapies—drugs that prevent protein translation from terminating prematurely. A new ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

This week, scientists at Meta, the firm behind Facebook and Instagram, released the structures of more than 600 million putative proteins in a database called the ESM Metagenomic Atlas. The structures ...

To better understand how RNA in bacteria gives rise to protein -- and potentially target these processes in the design of new antibiotics -- researchers are turning their attention to the unique way ...

Aging is the main risk factor for dementia and Parkinson's disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function. But why does that happen? An ...

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, ...