When evaluating a patient with stable chest pain and no known coronary artery disease (CAD), how does the clinician decide whether to order imaging or other diagnostic tests? One approach involves a ...

Sequential conditional probability ratio tests (SCPRTs) provide monitoring procedures with a unique property that a decision reached at early stopping is unlikely to be reversed should the trial ...

We identified a cohort of anticancer drugs with a first registered efficacy trial from 2007 to 2011 on ClinicalTrials.gov. We downloaded all clinical trials for each included drug from the initiation ...

Fisher's exact probability test is severely conservative when interpreted with reference to conventional alpha levels due to the discontinuity of the sampling distribution for 2 × 2 tables. An ...