Researchers have discovered that the enzyme NUDT5 utilizes its structure to exercise metabolic control over a key pathway in ...

Drugs that interrupt the death of healthy bone cells and induce the death of cancerous cells located in bones can prevent or reduced cancer associated bone weakness and improve treatment outcomes for ...

Using human-induced pluripotent stem cell-derived kidney organoids, researchers from Science Tokyo uncovered how abnormal ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Tumors were eradicated in 30% of mice receiving cGAS LNPs injected into the tumor, in combination with immune checkpoint blockade.

Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One such pathway includes the stimulator of interferon genes (STING) pathway which acts ...

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of ...

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best ...

Chemotherapy kills cancer cells. But the way these cells die appears to be different than previously understood. Researchers have now uncovered a completely new way in which cancer cells die: due to ...