近日,中山大学医学院徐培教授团队在PML小体介导抗病毒天然免疫的研究中取得新进展,相关研究发表在微生物学权威学术期刊mBio(中科院一区,JCR Q1, IF 7.8)。该工作发现PML小体固有蛋白Sp100A能在细胞质中感应干扰素激活信号,并立即向细胞核发生转运。
Importantly, this unexpected intracellular localization of PML has been observed also in vivo through fractionation analysis of mouse liver cells (Giorgi, Pinton, and Pandolfi unpublished observations ...
本研究针对PML::JAK1融合肉瘤的形态学谱系与分子特征展开探索。研究人员通过报道全球第四例、首例伴KRASQ61H突变的病例 ...
本研究揭示了转录因子NFATc3与核支架蛋白PML(Promyelocytic Leukemia protein)在肿瘤发生中的新型互作机制。通过质谱(MS)、免疫 ...
The perfectly matched layer (PML) method is well-studied for acoustic scattering problems, electromagnetic scattering problems, and, more recently, elastic scattering problems, with homogeneous ...
We report the case of a 54-year-old woman with multiple sclerosis who was treated with delayed-release dimethyl fumarate (DMF; Tecfidera, Biogen Idec) and who died on October 13, 2014, from ...
一些您可能无法访问的结果已被隐去。
显示无法访问的结果