Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular detoxification. To perform ...

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding ...

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme ...

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...

Cryo-EM reconstructions of the human ATR–ATRIP complex show how clinical small-molecule inhibitors like VE-822 and RP-3500 bind to and inhibit ATR activity. A research team led by Prof. Gang Cai and ...

Human stem cells can differentiate into any human cell. But the process of dedifferentiation, essentially differentiation in reverse, is implicated in several diseases. Now researchers have uncovered ...

DALLAS – July 19, 2002 – UT Southwestern Medical Center at Dallas researchers, using X-ray crystallography, have discovered how a particular cell enzyme finds its target and clearly carries out its ...

Researchers have identified a new function of a well-known enzyme: the signal peptidase complex is responsible for the quality control of membrane proteins. The discovery of this new function for a ...

Chondrocytes play a crucial role in skeletal development. Many bones, such as those in the arms and legs, are formed through ...

The tree of life has three branches: archaea, bacteria, and eukaryotes. Eukaryotes include complex organisms, including plants, animals, and fungi. Eukaryotic cells contain many organelles, little ...