Researchers use mass spectrometry-based methods for single-cell proteomics, where they can identify and quantify thousands of proteins, proteoforms, and post-translational modifications within each ...

Mass spectrometry is a cornerstone technique across various scientific disciplines, enabling precise analysis of complex samples, characterization of atom clusters and molecules, and elucidation of ...

For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is seeing all the molecules in an intact tissue sample, down to the level of ...

Developing targeted small molecule quantitative workflows for clinical research presents many challenges to researchers. From determining the optimum methods needed to enhance selectivity and ...

To identify specific chemicals or molecules in the life sciences and medical research, scientists often use mass spectrometry (MS), usually paired with liquid chromatography (LC). These technologies ...

Perhaps no tool has been as instrumental to the proteomics revolution as the mass spectrometer. With the ability to deconvolute highly complex mixtures over a wide range of abundance levels, these ...

Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have developed a new method for studying the targets and effects of cancer drugs using data from discovery mass spectrometry (MS) ...

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University ...

Using additive manufacturing, MIT researchers produced a mass filter, which is the core component of a mass spectrometer, that is far lighter and cheaper than the same type of filter made with ...

A research team led by Prof. CHEN Chilai from Institute of Intelligent machines, Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS), developed the deep-sea mass ...