Upon entry into mitosis, loosely packed chromatin undergoes extensive compaction to form condensed chromosomes, which is essential for accurate segregation of genetic material and normal cell division ...

An international team of researchers co-led by Job Dekker, PhD, at UMass Chan Medical School, have identified rules that tell cells how to fold DNA into the tightly packed, iconic X-shaped chromosomes ...

This suggests that the chromosomes are formed by stacked layers of chromatin that are oriented perpendicular to the axis of the chromosome. This structure is very compact and probably has the function ...

The Artificial Chromosome Session provided an illuminating update on recent advances in chromosome engineering technology and potential downstream applications in the area of gene therapy. A ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Mitotic chromosomes are pivotal for the inheritance of genetic material. Now, it is already known that chromosomes vary in dimensions among organisms. But what governs mitotic chromosomal size and ...

UNIGE scientists reveal how separase, a key enzyme in cell division, ensures the accurate separation of chromosomes.

Scientists at Fred Hutchinson Cancer Research Center have worked out the molecular underpinnings of how chromosomes make the right number of crossovers — important links that make it possible for ...

Researchers have unveiled the evolutionary origin of the different chromosomal architectures found in three species of Agrobacterium. A comprehensive comparison of the Agrobacterium sequence ...

When it comes to DNA, one pesky mosquito turns out to be a rebel among species. Researchers at Rice University's Center for Theoretical Biological Physics (CTBP) are among the pioneers of a new ...