LCGC International Column Editor Michael Dong concludes his three-part series on HPLC fundamentals for practicing scientists with a case study concerning pharmaceutical development using UHPLC.

High-Performance Liquid Chromatography (HPLC) is a highly efficient analytical method used to separate, detect, and quantify components within complex mixtures. Based on chromatographic principles, ...

High-performance liquid chromatography or high-pressure liquid chromatography (HPLC) is a chromatographic method that is used to separate a mixture of compounds in analytical chemistry and ...

Plastic polypropylene vials showed minimal BAK adsorption loss, outperforming glass vials, including premium and silanized types. Benzalkonium chloride (BAK) is a common preservative composed of ...

The term liquid chromatography (LC) refers to a class of physicochemical methods which are used to separate and quantify compounds in a sample. LC is made up of a liquid mobile phase, which carries ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

Retention time and ion separation can be adjusted by altering eluent concentration and flow rate. Increasing the ...