Bone morphogenetic proteins (BMPs) have multiple roles in skeletal development, homeostasis and regeneration. BMPs signal via type I and type II serine/threonine kinase receptors (BMPRI and BMPRII).

What keeps bones able to remodel themselves and stay healthy? A team has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load. The ...

Breakthroughs, discoveries, and DIY tips sent every weekday. Terms of Service and Privacy Policy. For February, we’re focusing on the body parts that shape us ...

A new paper in JAMA Network Open determines whether type 2 diabetes mellitus (T2DM) increases the risk of fractures in older women. Diabetes affects over 500 million individuals worldwide, and its ...

Scientists are reporting the first direct evidence that a subtle change in the physical properties of a tissue can affect its function. The finding has immediate implications for understanding several ...

While research has uncovered many details about how blood cells function within bone marrow, the work of other cells existing in that space remained a relative mystery. Now, researchers from the ...

You’ve likely heard about vitamin D’s important role in maintaining strong bones and teeth. But it also plays several other important roles to keep your body healthy – including the function of your ...

Experiments in mice and observations in humans have suggested the bone protein osteocalcin acts as a hormone regulating, among other things, metabolism, fertility, exercise capacity and acute stress.