A schematic describing what Inocles do and where they’re found. It shows the kinds of roles its genes might have, and how those jobs could be connected to things happening in the human body.

Researchers have discovered giant DNA structures in oral bacteria, and data hint they could influence the function of your ...

Despite the diversity inherent to cancer, they all share a common theme: many things tend to go wrong. This can make it difficult to understand which factors are driving the cancer and which ones are ...

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection. These appear to ...

Most of an animal cell’s DNA is stored in its nucleus, packaged into chromosomes that help maintain order. But cancer cells often carry another type of DNA: molecules separate from the rest of the ...

Lukas Chavez uses multiomic techniques to study how extrachromosomal DNA (ecDNA) contributes to tumor heterogeneity and gene expression changes in medulloblastoma. In the 1960s, researchers in England ...

SAN DIEGO--(BUSINESS WIRE)--Boundless Bio, a clinical stage, next-generation precision oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver transformative therapies to ...

Extrachromosomal circular DNA (ecDNA) represents a distinct genomic entity that exists independent of the primary chromosomal structure. In cancer, ecDNA is recognised as a potent driver of oncogene ...

There is usually one bit of genomic DNA in a bacterial cell that encodes for most of its functions, but bacteria can carry other bits of genetic material like plasmids, which could carry a gene for ...

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA -- loops of DNA found outside of regular chromosomes -- are twice as ...

Research published in Nature Genetics on Oct.14, by Yale Cancer Center researchers at Yale School of Medicine, found a higher concentration of a specific kind of DNA — extrachromosomal or ecDNA — in ...