Protein structure and dynamics are intimately linked with biological activity. Understanding the physical basis for this activity requires knowledge of the equilibrium and kinetic properties of the ...

Researchers analyzed the role of NUDT5 and its interaction with other proteins in the folate pathway and in regulating purine synthesis.

Antimicrobial design; targeted protein degradation; mTORC1 inhibition; enzyme structure-function studies. My laboratory uses approaches derived from both chemistry and biology. Projects include ...

Researchers have made a significant advance toward the goal of using bacteria—rather than fossil fuels—to produce ethylene, a key chemical in the production of many plastics.

Acetolactate synthase, also known as acetohydroxyacid synthase (AHAS), is an enzyme involved in the branched chain amino acid biosynthesis pathway. AHAS is a thiamine diphosphate (ThDP)-dependent ...

This story is one in a series marking International Women and Girls in Science Day. Join us as we celebrate some laboratory leaders taking research to new heights. Enzymes are the fundamental stuff of ...