《Free Radical Biology and Medicine》：Platelet COX and LOX Enzymes Orchestrate Amyloid-β Secretion via RhoA Signaling: Implications for Neurodegenerative Diseases. 【字体： 大中小】 时间：2025年09月03日 来源：Free ...

Infection and injury cause controlled immune and inflammatory responses involving complex molecular signalling networks that lead to the production of bioactive lipid mediators. Eicosanoids are ...

本研究通过体外实验（ABTS/H2O2自由基清除、COX-2/5-LOX抑制）和计算机模拟（分子对接），首次揭示Hymenodictyon pachyantha叶片乙醇 ...

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large ...

COX-2 plays a pivotal role in ferroptosis during the progression of chronic liver disease, as it downregulates the Nrf2 signaling pathway, exacerbating ferroptosis, which is characterized by ferrous ...

Eicosanoids in non-small cell lung cancer (NSCLC). Background: Eicosanoids, including PGE-2 and 5-HETE, can increase blood levels of vascular endothelial growth factor (VEGF). Overexpression of COX-2 ...

A recently identified path of inflammation once thought to be wholly independent of other inflammatory systems has now been linked to another major pathway. The findings by neuroscientists at Johns ...

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking ...

Lipoxygenase (LOX) and lipid hydroperoxide-decomposing activity (LHDA) markedly increased in the fifth leaves of rice (Oryza sativa cv Aichiasahi) after infection with the rice blast fungus, ...

Environmental Health Perspectives, Vol. 115, No. 4 (Apr., 2007), pp. 513-518 (6 pages) Background: Arsenic contamination has become a major public health concern worldwide. Epidemiologic data show ...