Although naturally occurring proteins form stable defined tertiary structures, it is well known that many proteins with non-natural sequences have unstructured conformations 1,2. This suggests that ...

Imagining that protein stability needs to be kept within some limits for biological function is easy. However, is there any corresponding pressure on protein folding and, hence, the dynamic ...

Chromosome engineering is a major focus in the fields of systems biology, genetics, synthetic biology, and the functional analysis of genomes. Here, we describe the "telomerator," a new synthetic ...