Formulation characteristics must be optimized, following device selection, to achieve the desired performance for the capsule loaded in the dry powder inhaler. Capsules used in dry powder inhalers ...

Based on formulation simplicity and blinding capability, hard gelatin capsules are preferrable compared with other oral solid dosage forms, including tablets, in the early clinical phases of drug ...

Phase I study of imetelstat (GRN163L) in combination with paclitaxel (P) and bevacizumab (B) in patients (pts) with locally recurrent or metastatic breast cancer (MBC). Methods: In this randomized, ...

A more tamper-proof formulation of extended-release Oxycodone DETERx (Collegium Pharmaceutical Inc) could help to minimize abuse of the opioid drug. Topline results of a new study show that crushing ...

Increasing clarithromycin resistance is dramatically reducing the efficacy of standard triple therapy for Helicobacter pylori eradication. Quadruple therapy is associated with high cure rates, yet its ...

Objective: Spalt-Liqua® is a newsoft gelatin capsule containing 200mg of totally dissolved ibuprofen as the active ingredient. The primary objective of the study was to assess bioequivalence between ...

Cyclosporine has revolutionised the transplantation scene in the last 20 years by helping with immunosuppresion. Novartis have so far had the patent Cyclosporine has revolutionised the transplantation ...

In the Phase 2a obesity study, GSBR-1290 demonstrated a clinically meaningful and statistically significant placebo-adjusted mean decrease in weight of 6.2% 1 (p<0.0001) at 12 weeks. At Week 12, 67% ...