Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields. Now scientists are applying the technology's immense potential to human ...

Yi Li, professor of horticultural plant breeding biotechnology in the College of Agriculture, Health and Natural Resources ...

A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

CRISPR was one of the most influential breakthroughs of the last decade, but it's still imperfect. While the gene editing tool is already helping people with genetic ailments, scientists are also ...

本文报道了利用DNA-free CRISPR/Cas9技术对淀粉马铃薯品种"Kuras"中甾体糖生物碱（SGA）生物合成通路的关键基因进行定向编辑，成功获得SGA含量显著降低的突变体。研究靶向胆固醇合成前（SMO1-L、DWF1-L、DWF7-L）及合成后（16DOX、CYP88B1、TAMiso2）的6个关键基因，通过 ...

The discovery of CRISPR-Cas9’s gene-editing prowess revolutionized genetic engineering just over a decade ago. Now it appears that genetic engineering technology may be taking its next big leap.

Editing DNA with the same ease as spell-checking a Word document is a scientific holy grail. It would allow debilitating and deadly genetic diseases to not only be treated, but cured. The US Food and ...

At the end of 2023, the FDA approved Casgevy for sickle cell disease, its first approval for a therapeutic that used the genome editing tool clustered regulatory interspaced palindromic repeats ...

It's the go-to phrase for biologists who know more than they're telling. Ever since James Watson and Francis Crick ended their 1953 paper on the double helix by coyly saying "it has not escaped our ...